Global change is impacting wildlife around the world, making conservation of threatened species and environments paramount. State-of-the-art genomic methods can be used to better understand threatened species and to inform conservation management strategies (both in situ and ex situ). However, efficient conservation can only be achieved when science, policy and society work together. In this talk, I will highlight different modern genomic techniques and how they are being used for applied conservation and to inform policy. I will also show how some methods can be used for local capacity building, education and citizen-science to support conservation of threatened species and environments around the world.